Dr Neutsch, what are your most important goals in working with the PicoRaman?
We are evaluating the device directly “at the bioreactor”, i.e. for monitoring and analysing biotechnological cultures. Here, the time-controlled technology could offer advantages over currently established methods, especially when it comes to non-invasive, accurate estimation of quality-determining factors such as the concentration of the product formed.
What are your biggest challenges when you think about achieving these goals?
The first applications of the PicoRaman devices were more in the field of materials chemistry, and there are no ‘off-the-shelf’ connectivity solutions for biological systems yet. Technical development work still needs to be done here. In addition, the data provided by such Raman systems are usually not directly interpretable but require more or less extensive processing by suitable evaluation routines (keyword: computational methods, big data, machine learning). We must therefore create a suitable software framework to efficiently obtain the desired information.
Where do you see the greatest need for PicoRaman in the market?
There are several areas where Raman technology could open up even more potential if various interfering factors can be eliminated. The temporal gating option of the M3 PicoRaman offers a possible approach here. If successful, large subsectors of the bio-based industry, e.g. in the field of biotechnological production, would be interested in such improved, easy-to-implement measurement technologies.
Why did you choose Timegate’s PicoRaman M3 and what is particularly important to you?
It is about the technical advancement through the temporal control of the signal, which is only available in this device and could help us to better deal with certain interfering factors.
In addition to the improved signal specificity mentioned above, certain aspects of handling (hygienic design, robustness, mobility in the laboratory) must be given in order to be able to use the device to its full extent in our field of application.
How satisfied were you with the installation?
Very, the support was direct and very customised. You can tell that the company (Timegated) is not very experienced in sales presentations in some cases, but that gives it a friendly, personal touch.
How satisfied were you with the sales advice? What did you particularly like about it? Where do you think there is still potential for development?
Very professional, fast and flexible. Satisfied all round, we would say from the customer’s point of view. With more sales towards Switzerland (which is hoped for), the specific export/customs clearance routines could be better implemented.
Would you recommend PHI-GmbH to a friend?